Best Fishing Spots in South Carolina (2026) — Santee Cooper & Charleston

Top SC fishing: Santee Cooper world-class giant catfish, Lake Murray striped bass, Charleston Harbor tailing redfish, Lake Hartwell bass.

From the mountain streams of the upstate to the legendary Santee Cooper lakes and the massive tidal marshes of the Lowcountry, South Carolina is a fishing paradise. A simple $10 SC fishing license unlocks all inland waters.

South Carolina Striper Fishing

The Lowcountry (Requires Marine/Saltwater License)

SpotRegionSpeciesWhy Famous
Charleston HarborCoastRed Drum, SeatroutIncredible sight-fishing for tailing redfish in the grass
Myrtle Beach PiersGrand StrandSpanish Mackerel, KingGreat ocean access without owning a boat
Beaufort MarshesSouthern CoastCobia, TarponWorld-class tidal fishing in pristine estuaries

The Legendary Reservoirs (Requires Freshwater License)

WaterRegionSpeciesNotes
Santee CooperCentral SCCatfish, StripersLakes Marion & Moultrie form a legendary catfish factory
Lake MurrayColumbia AreaStriped Bass, BassMassive, clear water reservoir with top-tier tournaments
Lake HartwellUpstate / GA BorderSpotted Bass, StriperHosted the Bassmaster Classic multiple times
Lake WatereeCamden AreaCrappie, BassOne of SC's oldest and most fertile lakes

Seasonal Guide

SeasonBest TargetsPrime SpotsTips
Spring (Mar–May)Bass Spawn, CobiaLake Hartwell, BeaufortThe spring Cobia run in Broad River is epic
Summer (Jun–Aug)Mahi, Summer StripersOffshore CharlestonTroll deep on Lake Murray for schooling stripers
Fall (Sep–Nov)Bull Redfish, CrappieCharleston Harbor, WatereeThe fall bite in the salt marshes is aggressive and fun
Winter (Dec–Feb)Trophy Blue CatfishSantee CooperCut bait on the bottom of Lake Moultrie for 60lb+ cats!

Neighboring: North Carolina for Wylie/Wateree river systems, Georgia for Lake Hartwell and the Savannah River.

An SC annual freshwater license is $10. See full costs or buy yours.